“Deconstructing Memory Circuits at Cell Type-specific Resolution”
Nelson Spruston, Ph.D.
Senior Director, Scientific Programs; Laboratory Head
Janelia Research Campus
Howard Hughes Medical Institute
Nelson Spruston studies the hippocampus, with an emphasis on uncovering the diversity and complexity of cells and synapses that allow this brain structure to contribute to memory-guided behavior, such as spatial navigation and emotional responses. Spruston and his team use a combination of approaches – including a variety of imaging methods, next-generation RNA sequencing, in vitro and in vivo electrophysiology, and behavior – to study the diversity of cell types in the mouse hippocampus. Spruston’s research has implications for understanding how memories are stored and recalled, as well as diseases that affect these processes.
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